Provisional Program (Times are AEDT – Melbourne, Sydney, Canberra)
| Time | Tuesday 24 November | Wednesday 25 November | Thursday 26 November |
| Welcome 10:25 – 10:30 | Welcome and housekeeping John Whitelock & Brooke Farrugia | Welcome and housekeeping Brooke Farrugia | Welcome and housekeeping Brooke Farrugia |
| 1st Session 10:30-12:15 | Frontiers in Matrix Biology Chairs: John Whitelock & Brooke Farrugia 10:30 – 11:00 Tony Weiss (USyd) ‘Elastic molecules and accelerated tissue repair’ 11:00 – 11:15 Zhenjun Deng (UWA) ‘The Impact of Matrix Stiffness on Keloid and Normal Fibroblasts’ 11:15 – 11:30 Michael Papanicolaou (Garvan) ‘Mapping the Extracellular Matrix Through Breast Tumour Progression’ 11:30 – 11:45 Fatemeh Karimi (UNSW) ‘Nano-Scale Design of Cardiovascular Biomaterials’ 11:45 – 12:00 Rapid Fire Presentations 11:45 – 11:48 Shouyuan Jiang (UNSW) ‘Bioengineered Domain V of human perlecan for enhanced angiogenesis’ 11:48 – 11:51 Hayley Stent (UOtago) ‘Does Fish Muscle Hold Secrets to Improving Muscle Regeneration?’ 11:51 – 11:54 Ian Peall (QUT) ‘Investigating HSPGs in neural lineage specification’ 11:54 – 11:57 Louise Croizat-Viallet (UOtago) ‘Can the extracellular matrix composition impact preadipocyte functionality and healing capacity?’ 12:00 – 12:15 Questions for Rapid Fire Presenters | Therapies & Clinical Advances Chair: Megan Lord 10:30 – 11:00 Shenda Baker (Synedgen) ‘Glycopolymer interactions with the glycocalyx to modulate innate immune responses after dermal injury’ 11:00 – 11:15 Hanif Haidari (UniSA) ‘Antibiofilm efficacy of a multifunctional AgNP hydrogel for treatment of S. aureus infection in vivo with accelerated wound healing outcomes’ 11:15 – 11:30 Kieran Lau (UNSW) ‘Biofunctionalisation of gas-plasma modified silk biomaterials towards biomimetic vascular conduits’ 11:30 – 11:45 Jessica Chitty (Garvan) ‘LOX family inhibition improves response to standard of care therapy in desmoplastic pancreatic cancer’ 11:45 – 12:00 Rapid Fire Presentations 11:45 – 11:48 Aleksandra Butenko (Sechenov Uni) ‘NO-containing gas flow accelerates wound healing by 7 days’ 11: 48 – 11:51 Kallyanashis Paul (Hudson Inst) ‘Vaginal delivery of adult stem cells in Aloe vera-alginate hydrogel alleviates childbirth trauma in a rat model’ 11:51 – 11:54 Xuan Huang ‘Targeting Syndecan-1 to Reduce Mammographic Density; Potential roles in Detection, Prevention and Therapy of Breast Cancer’ 12:00 – 12:15 Questions for Rapid Fire Presenters |  Inflammation & Chronic Wounds Chair: Zlatko Kopecki 10:30 – 10:45 Jennifer Flegg (UniMelb) ‘The mathematics of wound healing’ 10:45 – 11:00 Zahra Lotfollahi (UAdelaide) ‘Anti-inflammatory properties of high-density lipoproteins in diabetic wound healing’ 11:00 – 11:15 Cindy Shu (Kolling Inst) ‘Joint inflammation in post-traumatic osteoarthritis in mice with aggrecan resistant to matrix metalloproteinase (MMP) cleavage’ 11:15 – 11:30 Nicole Garcia (Alfred) ‘Wound-matrix interactions in murine full-thickness wounds: how do BTM and FTSG heal a wound?’ 11:30 – 11:45 Brooke Farrugia (Uni Melb) ‘The role of glycosaminoglycans and their degrading enzymes in inflammatory cell homeostasis’ 11:45 – 12:00 Rapid Fire Presentations 11:45 – 11:48 Patrick Haubruck (Kolling Inst) ‘Evaluating the role of pro-inflammatory T-cell and macrophage subsets as part of the cellular immune response during the onset and development of posttraumatic osteoarthritis in mice.’ 11:48 – 11:51 Savannah Aitcheson (QUT) ‘Predicting complications in people with Type 1 and Type 2 Diabetes’ 11:51 – 11:54 Adriana Zanca (UniMelb) ‘Multicellular computational model of collective cell migration with an irregular free boundary’ 11:54 – 11:57 Justin Farrell (Kolling Inst) ‘Establishing a novel activated Th0/joint-tissue co-culture system to investigate osteoarthritis pathogenesis’ 12:00 – 12:15 Questions for Rapid Fire Presenters |
| Networking Session 12:15 – 13:00 | 12:15 – 12:45 Networking 12:45 – 13:00 Break (food / drink ) | 12:15 – 12:45 Networking 12:45 – 13:00 Break (food / drink ) | 12:15 – 12:45 Networking 12:45 – 13:00 Break (food / drink ) 12:50 – 13:00 ConvaTec Sponsored Presentation Dale Edwick (Fiona Stanley Hospital) ‘Electrical stimulation improves healing in acute minor burn injury, as measured by bioimpedance spectroscopy: A single centre, randomised, controlled trial’ |
| 2nd Session 13:00 – 14:45 | Cancer and Metastasis Chair: Larisa Haupt 13:00 – 13:15 Tom Cox (Garvan) ‘Matrix remodelling in solid tumour progression and metastasis’ 13:15 – 13:30 Brooke Pereira (Garvan) ‘Quantitative proteomics reveals cancer cell genotype can drive matrisomal changes associated with aggressive disease in pancreatic ductal adenocarcinoma (PDAC)’ 13:30 – 13:45 Sarah Boyle (UniSA) ‘Breast cancers reprogram stromal fibroblasts to promote tumour progression via remodelling of the microenvironment’ 13:45 – 14:00 Laura Bray (QUT) ‘Dissecting the role of tissue-specific cancer-associated fibroblasts in the prostate tumour microenvironment’ 14:00 – 14:15 Elysse Filipe (Garvan) ‘Matrix Stiffness alters Metastatic Potential of Breast Cancer Cells through Metabolic re-wiring’ 14:15 – 14:30 Rapid Fire Presentations 14:15 – 14:18 Shona Ritchie (Garvan) ‘A multi-omics approach to dissect the impact of the cancer cell-derived ECM during pancreatic cancer tumourigenesis’ 14:18 – 14:21 Lu Fu (UNSW) ‘The effects of heparin conjugated cerium oxide nanoparticles on angiogenesis’ 14:21 – 14:24 Thomas Molley (UNSW) ‘Freeform Printing of Tumor Invasion Models within Cell-laden Microgel Matrices’ 14:24 – 14:27 Amelia Parker (Garvan) ‘Extracellular Matrix Remodelling Defines Aggressive Non-Small Cell Lung Cancer’ 14:30 – 14:45 Questions for Rapid Fire Presenters |  Tissue Repair & Fibrosis Chair: Brooke Farrugia 13:00 – 13:30 Shuhei Yamada (Meijo Uni) ‘Congenital Disorders Caused by Defects in Biosynthesis of Glycosaminoglycans’ 13:30 – 13:45 Samantha Stehbens (UQ) ‘+TIP-dependent Tuning of Microtubule Mechanical Flexibility Protects Cells Navigating Confined Environments’ 13:45 – 14:00 Cory Xian (UniSA) ‘Enhanced Bone Morphogenetic Protein Signalling Causes Injury Site Bony Repair and Adjacent Uninjured Region Hypertrophic Change in the Injured Growth Plate Cartilage’ 14:00 – 14:15 Akaiti James (UWA) ‘Fibroblast heterogeneity within keloid scars: functional studies of subpopulations’ 14:15 – 14:30 Rapid Fire Presentations 14:15 – 14:18 Anna Trengove (UMelb) ‘Adhesive bioink for improved cartilage repair’ 14:18 – 14: 21 Clare Bandy (Harry Perkins Inst) ‘Circadian rhythm disruptions in wound healing after trauma’ 14:21 – 14:24 Subhajit Konar (U Auckland) ‘Role of matrix stiffness in tendon health and disease’ 14:24 – 14:27 Samantha Hefferan (Kolling Inst) ‘Histological Variations in Human Tendons’ 14:30 – 14:45 Questions for Rapid Fire Presenters |  Frontiers in Cutaneous BiologyChair: Pritinder Kaur 13:00 – 13:30 Fiona Wood (UWA) ‘Skin Regeneration: The Complexities of Translation into Clinical Practise.’ 13:30 – 13:45 Pritinder Kaur (Curtin U) ‘Investigating the heterogeneity of dermal pericytes’ 13:45 – 14:00 Zoe West (QUT) ‘Characterising MMP14 trafficking to reduce macrophage migration’ 14:00 – 14:15 Oliver Dreesen (A*STAR) ‘The role of heterochromatin in the accelerated ageing syndrome progeria’ 14:15 – 14:30 Rapid Fire Presentations 14:15 – 14:18 Caitlin Berry-Kilgour (U Otago) ‘Assessment of a bioactive hydrogel to improve healing and reduce scarring in a murine skin model.’ 14:18 – 14:21 Huan Ting Ong (Ear Science Inst) ‘Hypoxic regulation of wound healing activity from adipose-derived mesenchymal stem cells: Identifying wound healing targets using Ligand-Receptor Interactome’ 14:21 – 14:24 Helen Cao (U Otago) ‘Role of subcutaneous adipose tissue in surgical wound healing’ 14:30 – 14:45 Questions for Rapid Fire Presenters |
| Networking Session 14:45 – 19:00 | 14:45 – 16:00 Networking 16:00 – 17:00: AWTRS AGM (Zoom meeting) 17:00 – 18:00 Workshop – EMCRs Techniques Toolbox | 14:45 – 16:00 Networking 16:00 – 17:00: MBSANZ AGM (Link to Zoom meeting) | 14:55 – 15:15 Networking View our paper 15:15 – 15:30 Break (food / drink) |
| 3rd Session (Thursday) 15:30 – 16:45 | Regenerative Medicine & Stem Cells Chair: Brooke Farrugia 15:30 – 15:45 Rapid Fire Presentations 15:30 – 15:33 Ziyu Wang (USyd) ‘Tropoelastin-based peripheral arterial vascular graft for lower extremity revascularization’ 15:33 – 15:36 Jinia Lilanty (MCRI) ‘Skeletal disease-in-a-dish: Using induced pluripotent stem cells to model human cartilage disorders’ 15:36 – 15:39 Alexey Fayzullin (Sechenov Uni) ‘Pirfenidone inhibited peri-implant fibrosis through foreign-body giant cell repolarization: in vivo immunomorphological study’ 15:39 – 15:42 Osvaldo Contreras (Victor Chang) ‘PDGF/PDGFR signalling modulates the activation, differentiation and migration of skeletal muscle myoblasts’ 15:45 – 16:00 Questions for Rapid Fire Presenters 16:00 – 16:15 Shireen Lamande (MCRI) ‘Using induced pluripotent stem cells to model human skeletal development and disease’ 16:15 – 16:30 Andrew Cox (Peter Mac) ‘Exploring Nrf2’s role in adaptive remodelling of metabolism during liver regeneration.’ 16:30 – 16:45 Yu Suk Choi (UWA) ‘Mechanobiology in 3D: volume adaptation controls stem cell mechanotransduction and differentiation‘ | ||
| 16:45 – 17:15 Awards and closing remarks AWTRS Awards Presentation: Brooke Farrugia MBSANZ Awards Presentation: Megan Lord Closing Remarks: Brooke Farrugia & John Whitelock | |||
| 3rd Session 19:00 – 20:45 | Frontiers in Matrix Biology Chair: John Whitelock 19:00 – 19:15 Rapid Fire Presentations 19:00 – 19:03 Chloe Yeung (U Copenhagen) ‘Day-to-night changes in expression of clock genes in human tendon indicate a conserved circadian clock’ 19:03 – 19:06 Shuji Mizumoto (Meijo U) ‘A skeletal dysplasia with advanced bone age is caused by pathogenic variants in CSGALNACT1’ 19:06 – 19:09 Dylan Ashton (Kolling Inst) ‘The Effects of Decellularisation and Sterilisation on Kangaroo Xenograft Strength’ 19:09 – 19:12 Ben Ventura (Kolling Inst) ‘A comparative study of the degradation rate of lower limb tendons when exposed to bacterial collagenase’ 19:15 – 19:30 Questions for Rapid Fire Presenters 19:30 – 19:45 Jelena Rnjak-Kovacina (UNSW) ‘A Biomimetic Approach Toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of human Perlecan is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials’ 19:45 – 20:00 Jiao Jiao Li (UTS) ‘Interactions of stem cells in an in vitro model of an osteoarthritic joint’ 20:00 – 20:30 Karl Kadler (U Manchester) ‘Regulation of collagen homeostasis: intracellular pathways, circadian clock, and drug screens’ | Frontiers in Cutaneous & Matrix Biology Chair: Megan Lord 18:30 – 19:00 Barry Preston Award Presentation: Chris Parish (ANU) ‘Heparanase and heparan sulphate: the love of a lifetime’ Chair: Brooke Farrugia 19:00 – 19:15 Rapid Fire Presentations 19:00 – 19:03 Audrey Wang (A*STAR) ‘Identification and Quantification of Senescent Cells In UV-induced Skin Pathologies’ 19:03 – 19:06 Michael Yang (UMelb) ‘Decellularized extracellular matrices on substrates of variable stiffness improve mesenchymal stromal cell function and phenotype’ 19:06 – 19:09 Parinaz Ahangar (UniSA) ‘Therapeutic potential of Multipotent adult progenitor cells secretome for cutaneous wound treatment’ 19:15 – 19:30 Questions for Rapid Fire Presenters 19:30 – 19:45 Anna Guller (UNSW) ‘The role of extracellular matrix architecture in cancer colonization of the organs: the lessons from 3D engineered tumour models’ 19:45 – 20:15 Sara Wickstrom (U Helsinki) ‘Regulation of stem cell fate by mechanical forces’ 20:15 – 20:45 Patricia Rousselle (CNRS) ‘The epidermal basement membrane and its adaptability to the regeneration process: epithelial podosomes lead the way‘ | |
| Evening Activity | Informal networking sessions | 20:45 – 21:45 Trivia |
